Firefly Luciferase mRNA (ARCA, 5mCTP, ψUTP)

Catalogue Number: R1005-APE

Manufacturer:Apexbio
Type:mRNA
Shipping Condition:Dry Ice
Storage Condition:-70°C
Unit(s): 1 mg, 100 ug, 5 x 1 mg

Description

Description: Firefly Luciferase mRNA (ARCA, 5mCTP, ψUTP) expresses luciferase protein which is initially extracted from firefly Photinus pyralis. The enzyme catalyzes ATP-dependent D-luciferin oxidation to yield oxyluciferin, a singlet-excited compound that emits light when returning to its ground state. Firefly Luciferase is a frequently used bioluminescent reporter for gene regulation and function study. It is applicable in assays for gene expression, cell viability and in vivo imaging etc. Our Firefly Luciferase mRNA is provided at a concentration of 1mg/ml, it is ARCA capped, polyA-tailed and incorporated with modified nucleotides. The capping of ARCA (anti-reverse cap analog) ensures high translation efficacy, while the addition of 5mCTP/ψUTP and poly(A) tail reduces host cell immune response and enhance mRNA stability.

Additional Text

Short Description

Better performance of firefly luciferase mRNA modified by ARCA, 5mCTP and ψUTP, inhibiting RNA-mediated innate immune activation, stable and efficient expression efficiency, used as an experimental control.

Storage Note

-40°C or below

Price
839.00


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