EZ Cap™ Cas9 mRNA (5-moUTP)
Catalogue Number: R1015-APE
| Manufacturer: | Apexbio |
| Type: | mRNA |
| Shipping Condition: | Dry Ice |
| Storage Condition: | -70°C |
| Unit(s): | 1 mg, 100 ug, 5 x 1 mg |
Description
Description: The Cas9/guide RNA (Cas9/gRNA) system is commonly used for genome editing. Upon delivery of these components to the nucleus of a cell, the RNA guide sequence targets the site of interest and the Cas9 protein is employed to perform the DNA cleavage. 5moUTP-modified Cas9 mRNA is capped using Cap 1, a novel co-transcriptional capping method, which yields natural Cap 1 with high capping efficiency. 5moUTP modification reduces innate immune responses and increases Cas9 activity.
Additional Text
Short Description
Used with guideRNA for site-specific DNA cleavage in genome editing.
Storage Note
-40°C or below
R1015 MSDS
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