Catalogue Number: R1015-APE
|Shipping Condition:||Dry Ice|
|Unit(s):||1 mg, 100 ug, 5 x 1 mg|
Description: The Cas9/guide RNA (Cas9/gRNA) system is commonly used for genome editing. Upon delivery of these components to the nucleus of a cell, the RNA guide sequence targets the site of interest and the Cas9 protein is employed to perform the DNA cleavage. 5moUTP-modified Cas9 mRNA is capped using CleanCap, a novel co-transcriptional capping method, which yields natural Cap 1 with high capping efficiency. 5moUTP modification reduces innate immune responses and increases Cas9 activity.
Used with guideRNA for site-specific DNA cleavage in genome editing.