RANTES (Regulated on Activation, Normal T-cell Expressed and Secreted) (MaxLight 650)

Catalogue Number: R1100-11-ML650-USB

Manufacturer:	United States Biological
Type:	Monoclonal Primary Antibody - Conjugated
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	8.PP.11
Isotype:	IgG2b, kappa
Immunogen:	Recombinant protein corresponding to human RANTES, expressed in E. coli.
Application:	WB, IHC, FLISA

Overview
Datasheets

Description

Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. RANTES (regulated upon activation, normal T-cell expressed and secreted) is a 70-amino acid CC chemokine originally cloned from T cell-specific sequences-enriched cDNA libraries. Both human and murine RANTES are chemotactic for monocytes. Human RANTES is also a chemoattractant for T cells and eosinophils, as well as an activator of basophils for histamine release and of eosinophils. It binds to CCR1, CCR3, CCR4 and CCR5 and is one of the major HIV suppressive factors produced by CD8+ T cells. In contrast to other CC chemokines, RANTES is only slowly expressed after activation of leukocytes. It is involved in a number of pathological conditions like chronic inflammation and autoimmune diseases. Recombinant RANTES protein induces a dose dependent inhibition of different strains of HIV 1, HIV 2, and simian immunodeficiency (SIV).

Additional Text

Gene ID

6352

Gene Name

CCL5

Uniprot ID

P13501

Purification

Protein A purified

Antibody Clonality

Monoclonal

R1100-11-ML650 Datasheet

Price

£645.00

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