ROR gamma T (RORC2, NR1F3, RORgammaT) (PerCP)

Catalogue Number: R1183-30E-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in sodium chloride, 0.5% BSA, 0.09% sodium azide. Labeled with Peridinin-Chlorophyll-Protein-Complex (PerCP). Absorption: 482-564nm. Emission: 675nm.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 Tests
Host name: Mouse
Clone: 11C47
Isotype: IgG2b
Immunogen: Synthetic peptide corresponding to Met1-Arg10 from human RORyt isoform.
Application: FC

Description

Description: Retinoic acid-related Orphan Receptor gamma (ROR-gamma, TOR, RORC; NR1F3) is a member of the orphan nuclear receptor family. ROR-gamma is expressed in the muscle, thymus, testis, pancreas, prostate, heart, and liver. ROR-gamma plays a role in thymocyte development and homeostasis. RORs bind to DNA as monomers on half-site elements with 5'A/T-rich extensions. An N-terminal isoform of ROR-gamma, RORgammaT, has been shown to be specifically expressed in the thymus. By direct ELISA, this clone has been shown to specifically recognize the RORgammaT isoform, and not RORC.

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene ID

6097

Gene Name

RORC

Uniprot ID

P51449

Specificity

Recognizes human ROR-gammaT. Species Crossreactivity: mouse.

Purification

Affinity Purified

Antibody Clonality

Monoclonal