Alpha-Synuclein, 1-95
Catalogue Number: S-1012-1-RPE
| Manufacturer: | rPeptide |
| Physical state: | Lyophilized |
| Type: | Other Proteins |
| Shipping Condition: | RT |
| Unit(s): | 0.5 mg |
Description
Description: A deletion mutant of α-synuclein (amino acids 1-95), which contains the N-terminal amphipathic domain and the NAC region. Alpha-Synuclein (α-Synuclein) is a 14 kD (140 amino acids) acidic presynaptic protein. It is a major component of Parkinson's disease aggregates and is implicated in the pathogenesis of Parkinson's Disease and related neurodegenerative disorders. α-Synuclein accumulates in the brains of sporadic Parkinson's disease patients as a major component of Lewy bodies, which are intraneuronal cytoplasmic inclusions characteristic of Parkinson's disease. α-Synuclein appears to associate with other proteins that aggregate and is found in β-amyloid plaques and neuritic tangles in Alzheimer's disease.
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