BC-1215

Catalogue Number: S0322-SEL

Manufacturer:Selleck Chemicals
Type:Other Inhibitors
Shipping Condition:Blue Ice
Unit(s): 25 mg, 5 mg

Description

Description: BC-1215 is an inhibitor of F-box protein 3 (Fbxo3, a ubiquitin E3 ligase component) with IC50 of 0.9 µg/mL and LC50 of 87 µg/ml for IL-1β release. BC-1215 inhibits the Fbxo3-TRAF activation pathway by destabilizing TRAF1-6.