SDHC (Succinate Dehydrogenase Cytochrome b560 Subunit Mitochondrial, Succinate Dehydrogenase Complex Subunit C, Integral Membrane Protein CII-3, QPs-1, CYBL, CYB560, SDH3) (Azide Free) (MaxLight 650)

Catalogue Number: S0553-26-ML650-USB

Manufacturer:United States Biological
Preservative:Azide-free
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 10B2463
Isotype: IgG2a, kappa
Immunogen: Full-length recombinant protein corresponding to aa1-170 of human SDHC with GST tag (AAH33626). MW of the GST tag alone is ~26kD.
Application: WB, IHC, FLISA

Description

Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. Several related pseudogenes are located in different genomic regions. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants encoding different isoforms have been described.

Additional Text

Gene Name

SDHC

Uniprot ID

Q99643

Gene ID

6391

Specificity

Recognizes human SDHC.

Purification

Protein A purified

Antibody Clonality

Monoclonal