Dactolisib (BEZ235)
Catalogue Number: S1009-SEL
| Manufacturer: | Selleck Chemicals |
| Type: | Other Inhibitors |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 mg, 1 g |
Description
Description: Dactolisib (BEZ235, NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor for p110α/γ/δ/β and mTOR(p70S6K) with IC50 of 4 nM /5 nM /7 nM /75 nM /6 nM in cell-free assays, respectively. Inhibits ATR with IC50 of 21 nM in 3T3TopBP1-ER cell. Dactolisib induces autophagy and suppresses HIV-1 replication. Phase 2.
Additional Text
Caution
FOR RESEARCH USE ONLY
S1009 MSDS
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