Sheep anti Human ELK rec tyr Kinase (Eph B1 Ext.)
Catalogue Number: S100P-EXA
| Manufacturer: | ExAlpha |
| Type: | Primary Antibody |
| Alias: | Eph B1 (ELK receptor) EXT; Tyrosine-protein kinase receptor EPH-2; Ephrin type B receptor 1; HEK6 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 250 ug |
| Host name: | Sheep |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | A GST fusion protein ephB1 (Elk receptor) corresponding to amino acid sequence 16-351 of the N terminal, extracellular region, and having a molecular weight of 116 kD |
| Application: | IP, WB |
Description
Description: The immunogen used for the anti-human ephB1 (Elk receptor) -EXT region was a GST fusion protein ephB1 (Elk receptor) corresponding to amino acid sequence 16-351 of the N terminal, extracellular region, and having a molecular weight of 116 kD. ephB1, previously known as Elk(eph-like kinase), is a receptor tyrosine kinase of the highly tissue restricted family of eph proteins. EphB1 and other ephB family members are type 1 membrane spanning proteins, comprised of immunoglobulin, fibronectin type III, and cysteine rich subdomains in the ecto domain, and the single uninterrupted cytoplasmic tyrosine kinase domain upstream of a carboxyterminal sterile alpha motif (SAM) domain. ephB family proteins bind ephrins of the B class, ligands that are also transmembrane spanning proteins capable of transmitting signals. ephB1 is expressed predominantly in developing neural structures in embryos, and in vascular epithelium of kidney, and other tissues. Upon binding to alternatively oligomerized ephrin B1, ephB1 signals regulation of cell attachment and cellcell assembly. Members of this protein family are implicated in neuronal and vascular cell targeting.
Additional Text
Gene Name
EPHB1
Uniprot ID
P54762
Gene ID
2047
Purification
Ammonium Sulfate Precipitated
Antibody Clonality
Polyclonal
Application Notes
Application: 1-10 ug/ml for Western Blotting and 10-20 ug/ml for Immunoprecipitation.
Storage Note
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations