Rapamycin
Catalogue Number: S1039-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 24 months |
| Molecular Formula: | C51H79NO13 |
| Type: | Other Inhibitors |
| Alias: | Sirolimus, AY-22989, NSC-2260804 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 mg, 25 mg, 5 mg, 10 mM/ 1 mL, 1 g |
Additional Text
Caution
FOR RESEARCH USE ONLY
Smile String
CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)O)C)C)O)OC)C)C)C)OC
Short Description
Rapamycin is a specific mTOR inhibitor with IC50 of ~0.1 nM in HEK293 cells.Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator and an immunosuppressant.
Storage Note
2 years -80 in solvent
Inhibitor Handling Instructions
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