Sunitinib malate
Catalogue Number: S1042-SEL
| Manufacturer: | Selleck Chemicals |
| Type: | Other Inhibitors |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 mg, 500 mg, 10mM (1mL in DMSO), 10 mg, 1 g |
Description
Description: Sunitinib malate is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM in cell-free assays, and also inhibits c-Kit. Sunitinib Malate effectively inhibits autophosphorylation of Ire1α. Sunitinib Malate increases both death receptor and mitochondrial-dependent apoptosis.
Additional Text
Caution
FOR RESEARCH USE ONLY
S1042 MSDS
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