Doxorubicin (DOX) HCl
Catalogue Number: S1208-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 24 months |
| Molecular Formula: | C27H29NO11.HCl |
| Type: | Antibiotics and Antimycotics |
| Alias: | Adriamycin, NSC 123127, Hydroxydaunorubicin HCl |
| Shipping Condition: | Blue Ice |
| Unit(s): | 10 mg, 100 mg, 25 mg, 10 mM/ 1 mL, 1 g |
Additional Text
Caution
FOR RESEARCH USE ONLY
CAS Number
25316-40-9
Smile String
CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)N)O.Cl
Short Description
Doxorubicin (DOX) HCl is an antibiotic agent that inhibits human DNA topoisomerase I and topoisomerase II with IC50s of 0.8 µM and 2.67 µM, respectively. Doxorubicin reduces basal phosphorylation of AMPK. Doxorubicin is used in the concomitant treatment of HIV-infected patients but is found to be at high risk of HBV reactivation.This product may precipitate when dissolved in PBS solution. It is recommended to prepare the stock solution in pure water and dilute with either pure water or saline to obtain the working solution.Doxorubicin (Adriamycin) HCl can be used to induce animal models of kidney disease.
Storage Note
2 years -80 in solvent
Molecular Formula
C27H29NO11.HCl
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