Camptothecin (CPT)
Catalogue Number: S1288-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 24 months |
| Molecular Formula: | C20H16N2O4 |
| Type: | Other Inhibitors |
| Alias: | Campathecin, (S)-(+)-Camptothecin,NSC-100880 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 mg, 500 mg, 10mM (1mL in DMSO), 1 g |
Additional Text
Caution
FOR RESEARCH USE ONLY
Smile String
CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O
Short Description
Camptothecin (CPT) is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 µM in a cell-free assay. Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways. Phase 2.
Storage Note
2 years -80 in solvent
Inhibitor Handling Instructions
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