Staurosporine (STS)
Catalogue Number: S1421-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 24 months |
| Molecular Formula: | C28H26N4O3 |
| Physical state: | Lyophilized |
| Type: | Other Inhibitors |
| Alias: | AM-2282, Antibiotic AM-2282 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 2 mg, 5 mg, 25 mg, 1 g, 10 mM/1 ml |
Additional Text
Caution
FOR RESEARCH USE ONLY
Smile String
CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC
Short Description
Staurosporine (STS) is a potent PKC inhibitor for PKCα, PKCγ and PKCη with IC50 of 2 nM, 5 nM and 4 nM, less potent to PKCδ (20 nM), PKCε (73 nM) and little active to PKCζ (1086 nM) in cell-free assays. Also shows inhibitory activities on other kinases, such as PKA, PKG, S6K, CaMKII, etc. Phase 3.
Storage Note
2 years -80 in solvent
Inhibitor Handling Instructions
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