Pomalidomide
Catalogue Number: S1567-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 24 months |
| Molecular Formula: | C13H11N3O4 |
| Type: | Ligand |
| Alias: | CC-4047 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 mg, 10 mM/ 1 mL, 200 mg, 1 g |
Additional Text
Caution
FOR RESEARCH USE ONLY
Smile String
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N
Short Description
Pomalidomide inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs. Pomalidomide can be utilized in PROTAC as a ligand for targeting E3 ligase and inhibiting the E3 ligase protein cereblon (CRBN). Pomalidomide promotes apoptosis and cell cycle arrest.
Storage Note
2 years -80 in solvent
Inhibitor Handling Instructions
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