Geldanamycin
Catalogue Number: S2713-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 24 months |
| Molecular Formula: | C29H40N2O9 |
| Type: | Other Inhibitors |
| Alias: | NSC 122750 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 5 mg, 50 mg, 10mM (1mL in DMSO), 1 g |
Additional Text
Caution
FOR RESEARCH USE ONLY
Smile String
CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)C)OC)OC(=O)N)C)C)O)OC
Short Description
Geldanamycin is a natural existing HSP90 inhibitor with Kd of 1.2 µM, specifically disrupts glucocorticoid receptor (GR)/HSP association. Geldanamycin attenuates virus infection-induced ALI (acute lung injury)/ARDS (acute respiratory distress syndrome) by reducing the host's inflammatory responses.
Storage Note
2 years -80 in solvent
Inhibitor Handling Instructions
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