PF-5274857
Catalogue Number: S2777-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 24 months |
| Molecular Formula: | C20H25ClN4O3S |
| Type: | Other Inhibitors |
| Shipping Condition: | Blue Ice |
| Unit(s): | 5 mg |
Additional Text
Caution
FOR RESEARCH USE ONLY
Short Description
PF-5274857 is a potent and selective Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 and Ki of 5.8 nM and 4.6 nM, respectively, and can penetrate the blood-brain barrier.
Smile String
CC1=CC(=C(N=C1)C2=CC(=NC=C2Cl)N3CCN(CC3)C(=O)CCS(=O)(=O)C)C
Storage Note
2 years -80 in solvent
Inhibitor Handling Instructions
SUPPORT
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