Tofacitinib
Catalogue Number: S2789-SEL
| Manufacturer: | Selleck Chemicals |
| Type: | Other Inhibitors |
| Shipping Condition: | Blue Ice |
| Unit(s): | 10 mg, 100 mg, 5 mg, 1 g |
Description
Description: Tofacitinib is a novel inhibitor of JAK3 with IC50 of 1 nM in cell-free assays, 20- to 100-fold less potent against JAK2 and JAK1. Tofacitinib inhibits the expression of antiapoptotic BCL-A1 and BCL-XL in human plasmacytoid dendritic cells (PDC) and induced PDC apoptosis.
Additional Text
Caution
FOR RESEARCH USE ONLY
S2789 MSDS
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