Catalogue Number: S2808-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 24 months |
| Molecular Formula: | C24H32ClN5O2 |
| Type: | Other Inhibitors |
| Alias: | RG7440 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 5 mg, 10 mM/ 1 mL, 100 mg, 25 mg |
FOR RESEARCH USE ONLY
Ipatasertib (GDC-0068, RG7440) is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM in cell-free assays, 620-fold selectivity over PKA. Phase 2.
CC1CC(C2=C1C(=NC=N2)N3CCN(CC3)C(=O)C(CNC(C)C)C4=CC=C(C=C4)Cl)O
2 years -80 in solvent