Triptolide
Catalogue Number: S3604-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 24 months |
| Molecular Formula: | C20H24O6 |
| Type: | Other Inhibitors |
| Alias: | PG490, NSC 163062 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg, 5 mg, 10 mM/1 ml, 1 g, 100 mg |
Additional Text
Caution
FOR RESEARCH USE ONLY
Short Description
Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii. It functions as a NF-κB inhibitor with dual actions by disruption of p65/CBP interaction and by reduction of p65 protein. Triptolide (PG490) abrogates the transactivation function of heat shock transcription factor 1 (HSF1). Triptolide inhibits MDM2 and induces apoptosis through a p53-independent pathway.
Storage Note
2 years -80 in solvent
Inhibitor Handling Instructions
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