Harmine hydrochloride

Catalogue Number: S3817-SEL

Manufacturer:	Selleck Chemicals
Type:	Other Inhibitors
Shipping Condition:	Blue Ice
Unit(s):	25 mg, 10 mM/1 ml

Overview
Datasheets

Description

Description: Harmine (Telepathine), a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds, is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60-fold higher IC50 value for DYRK2. Harmine also inhibits monoamine oxidases (MAOs), PPARγ and cdc-like kinases (CLKs). Harmine inhibits 5-HT2A serotonin receptor with Ki of 397 nM.

S3817 Datasheet