Catalogue Number: S4908-SEL
Manufacturer: | Selleck Chemicals |
Shelf Life: | 24 months |
Molecular Formula: | C22H20N2O5 |
Type: | Other Inhibitors |
Alias: | NK012 |
Shipping Condition: | Blue Ice |
Unit(s): | 10 mg, 50 mg, 10mM (1mL in DMSO), 1 g |
FOR RESEARCH USE ONLY
SN-38 (NK012) is an active metabolite of CPT-11, inhibits DNA topoisomerase I, DNA synthesis and causes frequent DNA single-strand breaks. SN-38 induces autophagy.
CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=C1C=C(C=C5)O
2 years -80 in solvent