B-Raf IN 1

Catalogue Number: S6538-SEL

Manufacturer:Selleck Chemicals
Shelf Life:36 months
Molecular Formula:C29H24F3N5O
Type:Other Inhibitors
Shipping Condition:Blue Ice
Unit(s): 2 mg

Additional Text

Short Description

B-Raf IN 1 is an inhibitor of Raf wih IC50 values of 24 nM and 25 nM for B-Raf and C-Raf respectively. It is selective over 13 other kinases, including PKCα, IKKβ, and PI3Kα.

Smile String

CN(C)CC1=CC=C(C=C1)C2=C3N=CC=C(N3N=C2)C4=CC(=CC=C4)NC(=O)C5=CC(=CC=C5)C(F)(F)F

Storage Note

3 years -20°C powder