DM1 (Mertansine)
Catalogue Number: S6773-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 36 months |
| Molecular Formula: | C35H48ClN3O10S |
| Type: | Other Inhibitors |
| Alias: | Maytansinoid DM1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 mg, 5 mg, 100 mg |
Additional Text
Short Description
DM1 (Mertansine), an antibody-conjugatable maytansinoid, is a selective microtubule inhibitor that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC).Solutions are unstable and should be fresh-prepared.
Smile String
COC1C=CC=C(C)CC2=CC(=C(Cl)C(=C2)OC)N(C)C(=O)CC(OC(=O)C(C)N(C)C(=O)CCS)C3(C)OC3C(C)C4CC1(O)NC(=O)O4
Storage Note
3 years -20°C powder
Inhibitor Handling Instructions
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