(+)-JQ1
Catalogue Number: S7110-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 24 months |
| Molecular Formula: | C23H25ClN4O2S |
| Type: | Biochemicals |
| Shipping Condition: | Blue Ice |
| Unit(s): | 10 mg, 25 mg, 10mM (1mL in DMSO), 100 mg, 1 g |
Additional Text
Caution
FOR RESEARCH USE ONLY
Short Description
(+)-JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4(1/2) in cell-free assays, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family. (+)-JQ1 suppresses cell proliferation via inducing autophagy. (+)-JQ1 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes.
Smile String
CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)OC(C)(C)C)C4=CC=C(C=C4)Cl)C
Storage Note
2 years -80 in solvent
Inhibitor Handling Instructions
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations