Catalogue Number: S7565-SEL
Manufacturer: | Selleck Chemicals |
Type: | Other Inhibitors |
Shipping Condition: | Blue Ice |
Unit(s): | 25 mg, 5 mg, 1 g, 10 mM/1 ml |
Description: WH-4-023 (KIN001-112, KIN112, Dual LCK/SRC inhibitor) is a potent and orally active Lck/Src inhibitor with IC50s of 2 nM and 6 nM in cell-free assays, respectively. Exhibits >300-fold selectivity against p38α and KDR. Also potently inhibits SIK (IC50 values are 10, 22 and 60 nM for SIK 1, 2 and 3 respectively) and displays selectivity over a range of closely related kinases.
FOR RESEARCH USE ONLY