STAT3 (Signal Transducer and Activator of Transcription 3, Acute-phase Response Factor, APRF) (Carboxyfluorescein)

Catalogue Number: S7971-02F-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid. Labeled with Carboxyfluorescein.
Type:Monoclonal Primary Antibody - Conjugated
Alias:acute-phase response factor|ADMIO|ADMIO1|APRF|DNA-binding protein APRF|HIES|signal transducer and activator of transcription 3
Shipping Condition:Blue Ice
Unit(s): 100 Tests
Host name: Mouse
Clone: 7H9
Isotype: IgG2b
Immunogen: Recombinant protein corresponding to Met1-Asn175 from human STAT3, expressed in E. coli.
Application: FC

Description

Description: Signal Transducer and Activator of Transcription (STAT) proteins are transcription factors activated in response to cytokine, growth factor, or hormone receptor signaling. Janus kinases (JAKs) phosphorylate STAT proteins and induce dimerization. Homo- or heterodimers translocate to the nucleus where they bind to DNA and activate transcription.

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene Name

STAT3

Gene ID

6774

Uniprot ID

P40763

Specificity

Recognizes human STAT3.

Purification

Protein A purified

Antibody Clonality

Monoclonal