Catalogue Number: S8041-SEL
Manufacturer: | Selleck Chemicals |
Physical state: | Lyophilized |
Type: | Other Inhibitors |
Shipping Condition: | Blue Ice |
Unit(s): | 5 mg, 25 mg, 100 mg, 10mM (1mL in DMSO), 1 g |
Description: Cobimetinib (GDC-0973, RG7420) is a potent and highly selective MEK1 inhibitor with IC50 of 4.2 nM, and showing no significant inhibition when tested against a panel of more than 100 of serine-threonine and tyrosine kinases. Cobimetinib induces apoptosis. Phase 3.