dBET1
Catalogue Number: S8296-SEL
| Manufacturer: | Selleck Chemicals |
| Type: | Biochemicals |
| Shipping Condition: | Blue Ice |
| Unit(s): | 2 mg, 5 mg |
Description
Description: dBET1 is a CRBN-based BET degrader with an IC50 of 20 nM, showing highly selectivity. Out of 7,429 proteins, only the expression of the oncoproteins MYC and PIM1, as well as BRD2, BRD3 and BRD4 are significantly downregulated by dBET1 treatment.
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