Siremadlin (HDM201)
Catalogue Number: S8606-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 24 months |
| Molecular Formula: | C26H24Cl2N6O4 |
| Type: | Other Inhibitors |
| Alias: | NVP-HDM201 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg, 5 mg, 10 mM/1 ml |
Additional Text
Short Description
Siremadlin (HDM201) is a novel, highly potent and selective inhibitor of the p53-Mdm2 interaction with affinity constant for Mdm2 in the picomolar range and a selectivity ratio greater than 10000-fold vs Mdm4.
Smile String
CC(C)N1C2=C(C(=O)N(C2C3=CC=C(C=C3)Cl)C4=CC(=CN(C4=O)C)Cl)N=C1C5=CN=C(N=C5OC)OC
Storage Note
2 years -80 in solvent
Inhibitor Handling Instructions
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