S55746
Catalogue Number: S8759-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 36 months |
| Molecular Formula: | C43H42N4O6 |
| Type: | Other Inhibitors |
| Alias: | S 055746,BCL201 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 mg, 5 mg |
Additional Text
Short Description
S55746 (S 055746,BCL201) is a novel, orally active BCL-2 specific inhibitor (Ki = 1.3 nM) with poor affinity for BCL-XL and no significant binding to MCL-1, BFL-1 (BCL2A1/A1). The selectivity of S55746 for BCL-2 versus BCL-XL ranges from ~70 to 400 folds.
Smile String
C1CCN2C(=C(C=C2C3=CC4=C(C=C3C(=O)N5CC6=CC=CC=C6CC5CN7CCOCC7)OCO4)C(=O)N(C8=CC=CC=C8)C9=CC=C(C=C9)O)C1
Storage Note
3 years -20°C powder
Inhibitor Handling Instructions
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