Catalogue Number: S8760-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 36 months |
| Molecular Formula: | C25H27N3O5 |
| Type: | Biochemicals |
| Shipping Condition: | Blue Ice |
| Unit(s): | 2 mg, 25 mg, 5 mg, 10 mM/1 ml, 1 g, 100 mg |
Iberdomide (CC-220) is a novel oral immunomodulatory compound that targets cereblon, part of the CRL4CRBN E3 ubiquitin ligase complex, with an IC50 of 60 nM in a competitive TR-FRET assay. Iberdomide (CC-220) induces apoptosis with antitumor and immunostimulatory activities.
C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3OCC4=CC=C(C=C4)CN5CCOCC5
3 years -20°C powder