dBET6
Catalogue Number: S8762-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 36 months |
| Molecular Formula: | C42H45ClN8O7S |
| Type: | Biochemicals |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 mg, 5 mg, 10 mM/1 ml, 200 mg, 1 g |
Additional Text
Short Description
dBET6 is a highly cell-permeable PROTAC degrader of BET bromodomains with an IC50 of 14 nM for BRD4 binding. dBET6 also induces c-MYC downregulation and apoptosis.
Smile String
CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)NCCCCCCCCNC(=O)COC4=CC=CC5=C4C(=O)N(C5=O)C6CCC(=O)NC6=O)C7=CC=C(C=C7)Cl)C
Storage Note
3 years -20°C powder
Inhibitor Handling Instructions
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