Catalogue Number: S8790-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 36 months |
| Molecular Formula: | C29H25N3O4S |
| Type: | Other Inhibitors |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 mg, 5 mg, 10mM (1mL in DMSO), 1 g, 100 mg |
ML385 is a novel and specific NRF2 inhibitor with an IC50 of 1.9 µM. It inhibits the downstream target gene expression of NRF2. NRF2 regulates the activity of several ferroptosis and lipid peroxidation-related proteins.
CC1=CC=CC=C1C(=O)N2CCC3=C2C=CC(=C3)C4=C(SC(=N4)NC(=O)CC5=CC6=C(C=C5)OCO6)C
3 years -20°C powder