Homoharringtonine (HHT)
Catalogue Number: S9015-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 36 months |
| Molecular Formula: | C29H39NO9 |
| Type: | Other Inhibitors |
| Alias: | CGX-635, Myelostat, NSC 141633 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg, 5 mg, 10 mM/1 ml, 1 g, 100 mg |
Additional Text
Smile String
CC(C)(CCCC(CC(=O)OC)(C(=O)OC1C2C3=CC4=C(C=C3CCN5C2(CCC5)C=C1OC)OCO4)O)O
Short Description
Homoharringtonine (HHT), a plant alkaloid with antitumor properties, inhibits protein translation by preventing the initial elongation step of protein synthesis via an interaction with the ribosomal A-site. Homoharringtonine reversiblely inhibits IL-6-induced STAT3 Tyrosine 705 phosphorylation and reduced anti-apoptotic proteins expression.
Storage Note
3 years -20°C powder
Inhibitor Handling Instructions
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