Gambogenic acid
Catalogue Number: S9031-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 36 months |
| Molecular Formula: | C38H46O8 |
| Type: | Other Inhibitors |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg, 10 mg |
Additional Text
Short Description
Gambogenic Acid, identified from Gamboge, is an inhibitor of the FGFR signaling pathway in non-small-cell lung cancer (NSCLC) and exhibits anti-tumor effects. Gambogenic acid acts is also an effective inhibitor of EZH2 that specifically and covalently binds to Cys668 within the EZH2-SET domain, and triggers EZH2 ubiquitination.
Storage Note
3 years -20°C powder
Inhibitor Handling Instructions
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