TCR, alpha, beta (T Cell Receptor, T-cell Receptor beta-1 Chain C Region, TRBC1, T-cell Receptor alpha Chain C Region, TRAC, TCRA) (Biotin)

Catalogue Number: T2040-02N2-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, 0.09% sodium azide. Labeled with Biotin.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 500 ug
Host name: Hamster
Clone: H57-597
Isotype: IgG
Immunogen: TCR affinity purified from mouse T-cell hybridoma DO-11.10
Application: FC, IP, IHC

Description

Description: The alpha/beta TCR is expressed on T lymphocytes of all mouse strains tested. Plate-bound or soluble antibody activates a/b TCR-bearing T cells. In vitro and in vivo, this antibody can induce immature thymocytes to undergo apoptosis. In vivo administration of this antibody has been shown to deplete a/b TCR-bearing cells to near completion and prevent graft rejection.

Additional Text

Caution

FOR RESEARCH USE ONLY

Specificity

Recognizes common epitope of the beta chain of the mouse alpha/beta T cell receptor (TCR) complex. Does not react with gamma, delta TCR-bearing cells.

Purification

Purified

Antibody Clonality

Monoclonal