TCR, gamma, delta (T Cell Receptor) (PE)

Catalogue Number: T2040-05D-USB

Manufacturer:United States Biological
Physical state:Purified IgG conjugated to R. Phycoerythr(RPE) - liquid with 0.09% sodium azide, 0.5% BSA.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Hamster
Clone: GL3
Isotype: IgG
Immunogen: C57BL/6J intraepithelial lymphocytes
Application: FC

Description

Description: T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ belongs to the immunoglobulin superfamily, which is involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. γ/δ TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8- although some are CD8+. T cells expressing the γ/δ TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation.

Additional Text

Caution

FOR RESEARCH USE ONLY

Specificity

Reacts with mouse TCR gamma/delta. Species Crossreactivity: Not established.

Purification

Affinity Purified

Antibody Clonality

Monoclonal