Catalogue Number: T2040-05D-USB
| Manufacturer: | United States Biological |
| Physical state: | Purified IgG conjugated to R. Phycoerythr(RPE) - liquid with 0.09% sodium azide, 0.5% BSA. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Hamster |
| Clone: | GL3 |
| Isotype: | IgG |
| Immunogen: | C57BL/6J intraepithelial lymphocytes |
| Application: | FC |
Description: T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ belongs to the immunoglobulin superfamily, which is involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. γ/δ TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8- although some are CD8+. T cells expressing the γ/δ TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation.
FOR RESEARCH USE ONLY
Reacts with mouse TCR gamma/delta. Species Crossreactivity: Not established.
Affinity Purified
Monoclonal