TCR, gamma, delta (T Cell Receptor) (APC)
Catalogue Number: T2040-05L-APC-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC). |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Hamster |
| Clone: | GL3 |
| Isotype: | IgG |
| Immunogen: | C57BL/6J intra epithelial lymphocytes. |
| Application: | FC, IP, IHC |
Description
Description: T cell receptor (TCR) is a heterodimer consisting of an alpha and a beta chain (TCR a/b) or a g and a d chain (TCR g/d). TCR g/d belongs to the immunoglobulin superfamily, which is involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. g/d TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most g/d T cells are CD4-/CD8- although some are CD8+. T cells expressing the g/d TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that g/d T cells also play a principal role in antigen presentation.
Additional Text
Specificity
Recognizes mouse TCR gamma/delta expressing lymphocytes.
Purification
Affinity Purified
Antibody Clonality
Monoclonal
T2040-05L-APC Datasheet
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