TCR, gamma, delta (T Cell Receptor) (MaxLight 650)

Catalogue Number: T2040-05L-ML650-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™650.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Hamster
Clone: GL3
Isotype: IgG
Immunogen: C57BL/6J intra epithelial lymphocytes.
Application: IP, IHC

Description

Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. T cell receptor (TCR) is a heterodimer consisting of an alpha and a beta chain (TCR a/b) or a g and a d chain (TCR g/d). TCR g/d belongs to the immunoglobulin superfamily, which is involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. g/d TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most g/d T cells are CD4-/CD8- although some are CD8+. T cells expressing the g/d TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that g/d T cells also play a principal role in antigen presentation.

Additional Text

Specificity

Recognizes mouse TCR gamma/delta expressing lymphocytes.

Purification

Affinity Purified

Antibody Clonality

Monoclonal