Tetrahydrocannabinol (THC) (FITC)

Catalogue Number: T2970-21-FITC-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. No preservative added. No stabilizing proteins added. Labeled with Fluorescein isothiocyanate (FITC).
Type:	Monoclonal Primary Antibody - Conjugated
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	1.BB.948
Isotype:	IgG1
Immunogen:	8-Tetrahydrocannabinol-BSA.
Application:	FLISA, LF

Overview
Datasheets

Description

Description: Cannabinoids, a group of C21 compounds present in Cannabis sativa L., their carboxylic acids, analogs, and transformation products, are the active ingredients found in hasish and marihuana. (-)-trans-D9-tetrahydrocannabinol (D9-THC) is the major psychopharmacologically active component of cannabis. Cannabis affect cognition and memory, euphoria and sedation, and antinociception (analgesia) without the respiratory depression problems associated with opioid analgesics. D9-THC is also immunosuppressive and impairs cell-mediated immunity, humoral immunity and cellular defenses against a variety of infectious agents both in vivo and in vitro. To date, two sub-types of the G-protein coupled cannabinoid receptor, CB1 and CB2, have been identified. The first brain-derived endogenous cannabinoids, an unsaturated fatty-acid ethanolamide, arachidonylethanolamide (AEA, also called anandamide) was found in brain. AEA has higher affinity for the CB1 than for the CB2. THC is rapidly adsorbed by the lungs and almost completely metabolized. The major metabolite is 11-nor-delta-9-tetrahydrocannbinol-9-carboxylic acid and is found with other metabolites in plasma, feces, and urine. THC-metabolites can be detected within hours or exposure and may be detectable for several days. A cut-off level of 50ng/ml marijuana metabolites has been selected as the initial screening level by the US Dept. of Health.

Additional Text

Specificity

Recognizes THC (Cannabinoids) and metabolites. Does not crossreact with opiates, cocaine metabolite, amphetamines and phencyclidine.

Purification

Protein A purified

Antibody Clonality

Monoclonal

T2970-21-FITC Datasheet

Price

£819.00

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