Thrombospondin Type-1 Domain-containing Protein 1 (THSD1, Transmembrane Molecule with Thrombospondin Module, Tmtsp)

Catalogue Number: T5101-09-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a lyophilized powder from 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with sterile PBS, sterile 40-50% glycerol.
Type:	Monoclonal Primary Antibody - Unconjugated
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Mouse
Clone:	9j10
Isotype:	IgG1
Immunogen:	NS0-derived, recombinant human THSD1 (aa25-361).
Application:	FC

Overview
Datasheets

Description

Description: THSD1 (thrombospondin type 1 domain-containing protein 1; also TMTSP) is a 90-100kD type I transmembrane protein that is reminiscent of Unc5h proteins. It is expressed on embryonic endothelial and hematopoietic stem cells, and may be involved in cell-cell interactions. Mature human THSD1 contains a 388aa extracellular domain (ECD) (aa25-412) and a 418aa cytoplasmic region (aa434-851). The ECD possesses three Ig-like domains (aa156-316) and one TSP type-1 domain (aa340-393). There is one potential alternate start site at Met380, and two splice variants, one of which shows a deletion of aa341-393, and a second that shows a 36aa substitution for aa394-851, generating a soluble form. Over aa25-361, human THSD1 is 76% aa identical to mouse THSD1.

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene Name

THSD1

Specificity

Recognizes human THSD1. Species sequence homology: mouse (76%).

Purification

Protein G purified

Accession Number

NP_954872

Uniprot ID

Q9JM61

Antibody Clonality

Monoclonal

Gene ID

56229

T5101-09 Datasheet

Price

£754.00

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