TLR2 (Toll Like Receptor 2, Toll-like Receptor 2 Precursor, TLR 2, TLR-2, CD282, CD282 Antigen, Toll/interleukin 1 Receptor-like 4, TIL4, Toll/interleukin Receptor-like Protein 4) (PerCP)

Catalogue Number: T8050-10C-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in 1ml saline, 0.5% BSA, 0.09% sodium azide. Labeled with Peridinin-Chlorophyll-Protein-Complex (PerCP). Absorption: 482-564nm. Emission: 675nm.
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	CD282\|TIL4\|toll/interleukin-1 receptor-like protein 4\|toll-like receptor 2
Shipping Condition:	Blue Ice
Unit(s):	100 Tests
Host name:	Mouse
Clone:	9j13
Isotype:	IgG2a
Immunogen:	NS0 mouse myeloma cell line transfected with human TLR2
Application:	FC

Overview
Datasheets

Description

Description: Human Toll-Like receptor 2 (TLR2) is a 97kD, 766aa type I transmembrane glycoprotein of the Toll-like receptor family (TLR) of pattern recognition receptors. TLR2 is expressed on most leukocytes, endothelial cells and hepatocytes. It forms heterodimers with TLR1, TLR6, or in humans, TLR10, and recognizes lipoproteins and glycolipids from bacteria, mycoplasma, and yeast. Ligand recognition by TLR2 stimulates production of pro-inflammatory cytokines including TNF-a, IL-2, IL-6, IL-12, and MIP-2. The extracellular regions of human and mouse TLR2 share 67% aa identity.

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene Name

TLR2

Gene ID

7097

Specificity

Recognizes human TLR2. Species sequence homology: mouse (67%)

Purification

Protein G purified

Uniprot ID

O60603

Antibody Clonality

Monoclonal

T8050-10C Datasheet

Price

£793.00

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