TLR4 (Toll Like Receptor 4, CD284) (PE)
Catalogue Number: T8050-34-PE-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with R-Phycoerythrin (PE). |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 3F5 (HTA125) |
| Isotype: | IgG2a |
| Immunogen: | Ba/F3 cell line expressing TLR4 |
| Application: | FC, IP |
Description
Description: TLR4 has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS. This antibody has been demonstrated to block activation of monocytes with LPS. Removal of sodium azide is recommended prior to use in functional assays.
Additional Text
Specificity
Recognizes the human Toll like receptor 4 (TLR4) cell surface antigen. Species Crossreactivity: Rhesus monkey, porcine, canine and guinea pig.
Purification
Protein A purified
Antibody Clonality
Monoclonal
T8050-34-PE Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations