TRAcP (Tartrate-Resistant Acid Phosphatase Type 5, Tartrate-Resistant Acid ATPase)
Catalogue Number: T8266-95A-USB
| Manufacturer: | United States Biological |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | 9C5 |
| Isotype: | IgG2b, kappa |
| Immunogen: | Full length purified protein corresponding to human TRAcP. |
| Application: | ELISA, ICC, IP, WB, DB, IHC |
Description
Description: Tartrate-resistant acid phosphatase type 5 (TRAcP), also referred to as Acp5, is secreted by osteoclasts during bone resorption. Release of TRAcP was stimulated by resorbogenic cytokines and repressed by calcitonin (a resorption inhibitor). TRAcP is also known to be expressed in high quantities in active macrophages and dendritic cells and play an essential part in presenting antigens to T cells. Inactive TRAcP released from adipose tissue macrophages has been shown to bring on hyperplastic obesity, keeping lipid metabolism and insulin sensitivity normal.
Additional Text
Gene Name
ACP5
Gene ID
54
Purification
Protein G purified
Uniprot ID
P13686
Antibody Clonality
Monoclonal
T8266-95A Datasheet
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