Tumor Necrosis Factor alpha (TNFa) (Biotin)
Catalogue Number: T9160-13D-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, 0.09% sodium azide. Labeled with Biotin. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 ug |
| Host name: | Rat |
| Clone: | 3H3094 |
| Isotype: | IgG1, kappa |
| Immunogen: | Recombinant mouse TNFa expressed in E. coli. |
| Application: | ELISA, FC, ICC, WB, IHC, NT |
Description
Description: Tumor Necrosis Factor alpha (TNF-alpha) is a 17.3kD multi-functional pro-inflammatory cytokine primarily secreted by macrophages, but also produced by T and B lymphocytes, activated monocytes and fibroblasts. TNF-alpha exists in both a transmembrane and mature soluble form and has many biological properties, including activation of transcription factor NF-KappaB, the induction of apoptosis in various tumor cell lines and the stimulation of cell differentiation and proliferation under certain conditions. Studies have revealed a role for TNF-alpha in inflammation, septic shock, autoimmune disease and rheumatoid arthritis.
Additional Text
Caution
FOR RESEARCH USE ONLY
Specificity
Recognizes mouse Tumor Necrosis Factor alpha (TNFa). Species crossreactivity: chicken
Purification
Purified
Antibody Clonality
Monoclonal
T9160-13D Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations