Tyrosine, phosphorylated (Tyr) (Agarose)
Catalogue Number: T9228-75A-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in 1X Cell Lysis Buffer, 0.1mg/ml BSA, 50% glycerol. No preservative added. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ul |
| Host name: | Mouse |
| Clone: | 3A45(P-Tyr-100) |
| Isotype: | IgG1 |
| Immunogen: | Phospho-Tyr-containing peptides |
| Application: | IP |
Description
Description: Since the original observations that protein tyrosine kinases (PTKs) play critical roles in oncogenic transformation (1,2), it has become clear that both protein tyrosine kinases and phospho-tyrosine phosphatases control a wide range of critical biological processes (3,4). Antibodies specific for phospho-tyrosine (5,6) have been invaluable reagents in these studies. Exceptionally sensitive new tools for studying tyrosine phosphorylation and monitoring tyrosine kinase activity in high throughput drug discovery.
Additional Text
Caution
FOR RESEARCH USE ONLY
Specificity
Useful for immunoprecipitation of tyrosine-phosphorylated proteins. Immobilized via the conjugation of carbohydrates to cross-linked agarose hydrazide beads. Does not crossreact with proteins phosphorylated on serine or threonine.
Purification
Purified
Modification
Phosphorylated, Tyr
Antibody Clonality
Monoclonal
T9228-75A Datasheet
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