HRP Mouse Anti-human IgG (Fc) Antibody *EM-07, monoclonal*
Catalogue Number: V1031505-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Secondary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 0.1 mg |
| Host name: | Mouse |
| Clone: | EM-07 |
| Isotype: | |
| Immunogen: |
Description
Description: High affinity immunoglobulin γ Fc receptor I (IgG Fc receptor I) is a 49 kda transmembrane protein that can be found in the clathrin-coated endocytic vesicle membrane, plasma membrane and early endosome membrane of cells. It is alternatively called Fc-γ RIA(IgG Fc receptor I) and Fc-γ RI(IgG Fc receptor I). In humans, Fc-γ RIA plays a role in the upregulation of protein tyrosine kinase activity. It is the subject of comprehensive study due to the fact that it plays a role in the Fc-γ receptor signaling pathway involved in phagocytosis and interferon-γ-mediated signaling pathway. Sequencing of Fc-γ RIA has exemplified it contains 5 conserved structural units: extracellular, cytoplasmic, Ig-like C2-type 1, Ig-like C2-type 2 and Ig-like C2-type 3 domain. It is thought to be essential to immune response. It binds to IgG. And it plays an important role in organismal processes, in particular, immune response, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent and receptor-mediated endocytosis.
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
V1031505 Protocol
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