Biotin Mouse Anti-human TCR α/β Antibody *IP26, monoclonal*

Catalogue Number: V1032235-AAT

Manufacturer:AAT Bioquest
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 0.1 mg
Host name: Mouse
Clone: IP26
Isotype:
Immunogen:

Description

Description: T cell receptor α chain constant is a 18 kDa transmembrane protein that can be expressed in the integral component of membrane, plasma membrane and T cell receptor complex of cells. In Homo sapiens, T cell receptor α chain constant is the subject of intensive study due to the fact that it is a component of the T cell receptor signaling pathway. Sequencing of T cell receptor α chain constant has shown it contains 2 conserved structural units: Ig-like C1-type and cytoplasmic domain, and furthermore, aids in organismal processes, in particular, adaptive immune response. T cell receptor α chain constant is thought to be essential to immune response. Mutations and abnormalities in T cell receptor α chain constant have been thought to be involved with a number of diseases, for instance, immunodeficiency 7 (IMD7). Immunodeficiency 7, an autosomal recessive inheritancedisorder characterized by recurrent infections, lymphadenopathy and autoimmunity, has especially been of interest to scientists.

Additional Text

Antibody Clonality

Monoclonal

Storage Note

See Protocol|12 months