Catalogue Number: V1032235-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 0.1 mg |
| Host name: | Mouse |
| Clone: | IP26 |
| Isotype: | |
| Immunogen: |
Description: T cell receptor α chain constant is a 18 kDa transmembrane protein that can be expressed in the integral component of membrane, plasma membrane and T cell receptor complex of cells. In Homo sapiens, T cell receptor α chain constant is the subject of intensive study due to the fact that it is a component of the T cell receptor signaling pathway. Sequencing of T cell receptor α chain constant has shown it contains 2 conserved structural units: Ig-like C1-type and cytoplasmic domain, and furthermore, aids in organismal processes, in particular, adaptive immune response. T cell receptor α chain constant is thought to be essential to immune response. Mutations and abnormalities in T cell receptor α chain constant have been thought to be involved with a number of diseases, for instance, immunodeficiency 7 (IMD7). Immunodeficiency 7, an autosomal recessive inheritancedisorder characterized by recurrent infections, lymphadenopathy and autoimmunity, has especially been of interest to scientists.
Monoclonal
See Protocol|12 months