Rabbit anti Rat Potassium Channel
Catalogue Number: X1038-NMB
| Manufacturer: | Nordic MuBio |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | RK5, Shal1, Kcnd2, Potassium voltage-gated channel subfamily D member 2 |
| Shipping Condition: | RT |
| Unit(s): | 100 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | |
| Application: | IF, IP, WB |
Description
Description: Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to Icurrent in heart and current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits In response to membrane depolarization, Kv4.2 channels accumulate in the closed-inactivated state(s), from which they directly recover, bypassing the open state. Kv4.2 is a substrate for ERK in vitro and in vivo, and suggest that ERK may regulate potassium-channel function by direct phosphorylation of the pore-forming alpha subunit.
Additional Text
Gene Name
KCND2
Uniprot ID
Q63881
Gene ID
65180
Purification
Ammonium Sulfate Precipitated
Antibody Clonality
Polyclonal
Application Notes
Optimal antibody concentration should be evaluated by serial dilutions. Suggested Western Blot dilution 1:1000. Other applications: Immunoprecipitation, immunofluorescence.
Storage Note
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
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